Radiographic Contrast 1999-2001
AVAILABLE FOR
SELF-PACED LEARNING
Iodinated contrast media: minimizing thrombosis and nephropathy
http://www.theheart.org/index.cfm?doc_id=23430
Drs Wayne B Batchelor and Roxana Mehran explore the differences
between ionic and nonionic contrast media in the context of percutaneous
coronary intervention. This continuing medical education activity provides an
in-depth examination of the COURT trial, emphasizing the limitations of that
trial. The program also focuses on GP IIb/IIIa inhibitors and contrast media as
they affect thrombus generation
(CME credit: 2 hours, category 1).
[Supported by an educational grant from Tyco Healthcare — Mallinckrodt
Inc]
Editorial
Prevention of contrast nephropathy after cardiac catheterisation
C S R BAKER and L R I BAKER
Heart 2001;85 361-362
http://www.heartjnl.com/cgi/content/full/85/4/361
AVAILABLE FOR
SELF-PACED LEARNING
"Critical issues in the
choice of contrast media in PTCA"
Originally presented in May 1999; now
available as a CME activity. Dr Gilbert Deray and an international faculty
provide an in-depth examination of contrast agents as they relate to thrombotic
complications during coronary angiography (CME credit: 2 hours, category 1).
Find it at: http://www.theheart.org/index.cfm?doc_id=21354
[supported by an unrestricted educational grant from Mallinckrodt Medical]
Effectiveness of and adverse events after
percutaneous coronary intervention in patients with mild versus severe renal
failure
Rubenstein MH, et al.
Am J Cardiol 2001;87:856-60.
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&dopt=r&uid=11274940
Acute renal failure requiring dialysis after
percutaneous coronary interventions
Gruberg L, et al.
Catheter Cardiovasc Interv 2001;52:409-16.
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&dopt=r&uid=11285590
AHA 2000 Meeting Coverage
CME Cybersession
Optimizing the choice of contrast agent in coronary angiography
http://cme.cybersessions.org/dukeu-port11oct00/index.html
October 11, 2000
Drs James Tcheng (chair), Roxana Mehran, and Gilbert Deray discuss how to properly select a contrast agent in the cath lab and how to minimize the risks of contrast administration during
angiography.
Prevention of radiographic-contrast-agent-induced reductions in renal function by acetylcysteine
Tepel M et al.
N Engl J Med 2000;343:180-4
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&dopt=r&uid=0010900277
Prophylactic oral administration of the antioxidant acetylcysteine (600 mg orally twice
daily) and 0.45 percent saline intravenously, before and after administration of the contrast agent prevent the reduction in renal function induced by contrast agents in patients with chronic renal
insufficiency.
VIP Trial - Influence of a nonionic, iso-osmolar contrast medium (iodixanol) versus an ionic, low-osmolar contrast medium (ioxaglate) on major adverse cardiac events in patients undergoing percutaneous transluminal coronary angioplasty: A multicenter, randomized, double-blind study. Visipaque in Percutaneous Transluminal Coronary Angioplasty
Bertrand ME et al.
Circulation 2000;101:131-6
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&dopt=r&uid=0010637198
No significant differences were observed between the iodixanol and ioxaglate groups with regard to
MACE, although hypersensitivity and adverse drug reactions were significantly less frequent in patients who received
iodixanol.
COURT trial - Randomized trial of contrast media utilization in high-risk PTCA
Davidson CJ et al.
Circulation 2000;101:2172-7
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&dopt=r&uid=0010801758
In this contemporary prospective multicenter trial of PTCA in the setting of acute coronary
syndromes, there was a low incidence of in-hospital clinical events for both treatment
groups. The cohort receiving the nonionic dimer iodixanol experienced a 45% reduction in in-hospital MACE when compared with the cohort receiving
ioxaglate.
The prognostic implications of further renal
function deterioration within 48 h of interventional coronary procedures in
patients with pre- existent chronic renal insufficiency
Gruberg L, et al.
J Am Coll Cardiol 2000;36:1542-8.
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&dopt=r&uid=11079656
Effects of dopamine and aminophylline on
contrast-induced acute renal failure after coronary angioplasty in patients with
preexisting renal insufficiency
Abizaid AS, et al.
Am J Cardiol 1999;83:260-3, A5.
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&dopt=r&uid=10073832