Long Lesions 2000-2001

TCTMD Expert Presentations  
Long Coronary Lesions: Defining the Problem D. Mathey  
Long Lesion Stenting M. T. Rothman  

TCT 2001 Abstracts

ACC 2001 Webcast

CCT 2001 The Book
Chapter 9. Treating Diffuse Lesions

IVUS-Guided Stenting Reduces Restenosis Risk in Long Lesions: the TULIP Trial
presented by Pranobe V. Oemrawsingh, MD
http://www.tctmd.com/ct/enewsletter-20010322/$user_id/?send_to=http://www.tctmd.com/meeting-news/one.html?news_item_id=2022

LATE BREAKING CLINICAL TRIALS - SLIDE SET DIRECTLY FROM THE PRESENTER
TULIP: Stent Implantation in Long Coronary Artery Lesions: A Randomized Comparison of Guidance by Ultrasound or Angiography  http://www.tctmd.com/ct/enewsletter-20010322/$user_id/?send_to=http://www.tctmd.com/clinical-trials/breaking/one.html?presentation_id=162


A randomised trial of endoluminal reconstruction comparing the NIR stent and the Wallstent in angioplasty of long segment coronary disease: results of the RENEWAL Study
Nageh T, et al.
Am Heart J 2001;141:971-6
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11376312
Full text available at: http://cardiology.medscape.com/40256.rhtml?srcmp=card-071301

TCT 2000 Expert Presentation Slides

Long Lesion Stenting 
  by Rothman MT Click here to see the slides

Procedural results and late clinical outcomes after percutaneous interventions using long (> or = 25 mm) versus short (< 20 mm) stents
  Kornowski R || Leon MB
  J Am Coll Cardiol 2000;35:612-8
  http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&dopt=r&uid=0010716462
Retrospective study on 1226 consecutive patients who underwent a single vessel intervention using a single long (> or =25 mm, 116 patients) or short (<20 mm, 1110 patients) tubular-slotted stent. TLR at one year was 14.5% vs. 13.8% (p = 0.69), and TVR rate was 19.6% vs. 17.3% (p = 0.41) in the long vs. short stent group, respectively.

Importance of lesion length on new device angioplasty of native coronary arteries. NACI Investigators. New Approaches to Coronary Interventions
 Saucedo JF, et al.
Catheter Cardiovasc Interv 2000;50:19-25.
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&dopt=r&uid=10816274

Clinical and angiographic follow-up after single long GFX coronary stent implantation [see comments]
  Nakagawa Y || Nobuyoshi M
  Catheter Cardiovasc Interv 2000;50:40-7
  http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&dopt=r&uid=0010816278
In this study, 141 consecutive lesions treated with a single long (24 or 30 mm) GFX stent were compared to 66 consecutive lesions requiring a single short (12 or 18 mm) stent. Restenosis was 34.7% and 23.3% for long and short stents (P = NS), respectively. Restenosis is correlated with the stent length (10.0% for 12 mm, 26.0% for 18 mm, 31.3% for 24 mm, and 39.2% for 30 mm).

Late-Breaking Clinical Trial 
ADVANCE Trial (ADditional VAlue of NIR stents for treatment of long Coronary lEsion)
  Serruys PW  Presented at the TCT 2000 Meeting
In this trial, among patients with long lesions, despite better angiographic results for stented patients, MACE at 9 months was about the same for stent, balloon angioplasty and bailout groups. Patients had single de novo long lesions (>20 mm, <50 mm). With results characterized as "better than expected," the trial was stopped early with event-free survival at 86% and 81% for balloon and stented patients, respectively. Patrick Serruys, M.D., the principal investigator for the trial, deemed it likely that it will take brachytherapy or drug-eluting stents to bring about further improvement.

Click here to view the full article.

Click here for the slide set presented at TCT 2000.